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We outline a series of research initiatives to improve identification of RHD in administrative data thereby contributing to monitoring the RHD burden globally

In the warmer tropical regions of WA no seasonality was observed, but overall incidence of LLC presentations were higher

Prevention strategies in ARF endemic settings may be enhanced by targeting new members entering a community and children in environments of close contact

We propose that hydroxychloroquine could be repurposed to reduce the risk of rheumatic heart disease after acute rheumatic fever

We analysed the stimulation of J8 antibodies in response to infection, and the role of existing J8 antibodies in protection against subsequent infection

The authors present a variety of pressing clinical research questions on optimal RHD prevention and advanced care

The young age of the first infection with skin sores and scabies reflects the high disease burden in these communities

Poor sanitation facilities appear to be a major source of Salmonella Typhi in Fiji, with transmission by drinking contaminated surface water and consuming unwashed produce

Group A Streptococcus (GAS) or Streptococcus pyogenes is responsible for an estimated 500,000 deaths worldwide each year.

The age-standardized disability-adjusted life years rates in the Eastern Mediterranean Region are considerably higher than the global average