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Research

Independent and combined effects of airway remodelling and allergy on airway responsiveness

There was a positive relationship between the thickness of the airway smooth muscle layer with airway responsiveness, which was shifted upward in the presence of allergy

Research

Early life rhinovirus infection exacerbates house-dust-mite induced lung disease more severely in female mice

Early life rhinovirus infection influences the development of house-dust-mite induced lung disease in female, but not male mice

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Stiffness Mediated-Mechanosensation of Airway Smooth Muscle Cells on Linear Stiffness Gradient Hydrogels

In obstructive airway diseases such as asthma and chronic obstructive pulmonary disease (COPD), the extracellular matrix (ECM) protein amount and composition of the airway smooth muscle (ASM) is often remodelled, likely altering tissue stiffness. The underlying mechanism of how human ASM cell (hASMC) mechanosenses the aberrant microenvironment is not well understood.

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The effect of diesel exhaust exposure on blood-brain barrier integrity and function in a murine model

Epidemiological studies indicate that exposure to diesel exhaust (DE) is associated with vascular-based disorders.

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Emerging Early Life Environmental Exposures and Lung Development

In this review article we systematically summarize the evidence for an impact on lung development of 1) maternal ingestion of arsenic contaminated drinking...

Research

Biodiesel exhaust-induced cytotoxicity and proinflammatory mediator production in human airway epithelial cells

Our results show that canola biodiesel exhaust exposure elicits inflammation and reduces viability of human epithelial cell cultures in vitro when compared...

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A cross-sectional survey of environmental health in remote Aboriginal communities in Western Australia

Poor environmental health is prevalent in remote Aboriginal communities and requires further delineation to inform environmental health policy

Research

Is acamprosate safe to use in pregnancy, and can it mitigate the effects of alcohol consumption in pregnant mice?

Alexander Larcombe BScEnv (Hons) PhD Honorary Research Fellow Honorary Research Fellow Associate Professor Alexander Larcombe began work at The Kids

Research

Self-citation in American Physiological Society Journals

This study investigates the incidence of self-citation (authors citing their own work) for scholarly articles in ten journals published by the American...