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Visceral leishmaniasis (VL) is caused by Leishmania donovani and Leishmania infantum chagasi. Genome-wide linkage studies from Sudan and Brazil identified...

Undescended testes is associated with an increased risk of testicular cancer and male infertility, and decreased paternity

We provide new evidence to support current guidelines for orchidopexy before age 18 months to decrease the risk of future testicular cancer and infertility

Traits associated with CVD, CRD and T2D in Aboriginal Australians provide novel insight into function of Arylsulphatase A Pseudodeficiency variants

To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins

Overall the analyses do not suggest individual sequence variants account for differences in clinical outcome or adaptation to different hosts.

MMP1 is regulated by factors other than FLI1, and that the influence of IL-6 on MMP1 was independent of its effect on FLI1 in Leishmania braziliensis

Our results imply a role for IgG-mediated inflammation in determining delayed-type hypersensitivity associated with asymptomatic leishmaniasis

Resulting data represents the consequence of transcriptional regulation in each analyzed state of mammalian cells.

These results highlight how UNICORN can enable reliable, powerful, and convenient genetic association analyses without access to the individual-level data