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Early Life Ovalbumin Sensitization and Aerosol Challenge for the Induction of Allergic Airway Inflammation in a BALB/c Murine ModelThis protocol adapted an experimental animal model of disease for sensitization to ovalbumin during the immediate post-weaning period beginning at 21 days of age
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Developmental regulation of type 1 and type 3 interferon production and risk for infant infections and asthma developmentType 1 and 3 interferon response capacity appears strongly developmentally constrained at birth
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A marked shift in innate and adaptive immune response in chinese immigrants living in a western environmentThere is a marked shift in innate and adaptive immune responses in Chinese immigrants after living in a Western environment for several years
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Basophil counts in PBMC populations during childhood acute wheeze/asthma are associated with future exacerbationsOur findings suggest that the proportion of degranulated basophils can also be associated with recurrent exacerbations
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Persistent and compartmentalised disruption of dendritic cell subpopulations in the lung following influenza A virus infectionImmunological homeostasis in the respiratory tract is thought to require balanced interactions between networks of dendritic cell (DC) subsets in lung...
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Anti-infective proteins in breast milk and asthma-associated phenotypes during early childhoodThe impact of breast milk feeding on susceptibility to asthma in childhood is highly controversial, due in part to failure of the majority of studies in the...
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Low serum 25-hydroxyvitamin D concentrations associate with non-alcoholic fatty liver disease in adolescents independent of adiposityThis paper examined the link between low serum Vitamin D levels and development of non-alcoholic fatty liver disease (NAFLD) in adolescents between 14 and 17...
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Prevention - what is the most promising approach?This paper is an editorial comment by Professor Patrick Holt on the potential for developing early intervention strategies in children with allergies and asthma
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Size-Dependent Uptake of Particles by Pulmonary Antigen-Presenting Cell PopulationsThe respiratory tract is an attractive target organ for novel diagnostic and therapeutic applications with nano-sized carriers, but their immune effects and...
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Maternal Vitamin D Levels and the Autism Phenotype Among OffspringWe tested whether maternal vitamin D insufficiency during pregnancy is related to the autism phenotype.