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Ultraviolet radiation is the leading preventable cause of skin cancer, and early-life exposure increases long-term risk. Despite this, guidelines on sun protection for children and young people are inconsistent.
Little is known about how sun exposure may affect the maternal skin barrier during pregnancy when many hormonal and physiological changes occur. In this longitudinal observational study, 50 pregnant women were recruited at 18-24 weeks' gestation, 25 in summer-autumn, and 25 in winter-spring. At three time points in pregnancy at 18-24, 28-30, and 36-38 weeks' gestation, participants completed a validated sun exposure questionnaire and had skin permeability and surface pH measured on the volar forearm.
In this review article we systematically summarize the evidence for an impact on lung development of 1) maternal ingestion of arsenic contaminated drinking...
Vitamin D deficiency is a global public health problem and has been associated with an increased incidence and severity of many diseases including diseases...
Vitamin D may be essential for restricting the development and severity of allergic diseases and asthma, but a direct causal link between vitamin D...
In experimental models, both vitamin D3-dependent and vitamin D3-independent pathways have been implicated in the mechanisms of UVR-induced systemic...
Despite considerable advances, the exact mechanism whereby UVR can lead to changes in immune responses is not entirely clear at present, and no...
In this chapter, evidence for and evidence against the involvement of vitamin D in the immunoregulatory properties of UV radiation is presented.
The analysis of 25-hydroxyvitamin D3 (25(OH)D3) and related metabolites represents a considerable challenge for both clinical and research laboratories...
Ultraviolet radiation (UVR) from sunlight is immunomodulatory and the main source of vitamin D for humans.