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Applying causal inference and Bayesian statistics to understanding vaccine safety signals using a simulation study

Community perception of vaccine safety influences vaccine uptake. Our objective was to assess current vaccine safety monitoring by examining factors that may influence the availability of post-vaccination survey data, and thereby the specificity and sensitivity of existing signal detection methods.

Invasive Fungal Disease in Immunocompromised Children: Current and Emerging Therapies

In an era of expanding indications for iatrogenic immunosuppression, invasive fungal disease (IFD) remains a significant challenge in immunocompromised children, with case fatality rates ranging from 10 to 70%. Understanding of current recommendations and recent evidence is essential to guide optimal IFD management.

Our research

At the Wesfarmers Centre, we undertake research in five key areas of infections and immunisation to assist in children's health.

PATROL RSV Study

Researchers from The Kids Research Institute Australia would like to understand more about respiratory syncytial virus (RSV) and how we can provide the best protection for kids.

Hospital-based research

Review the hospital-based research that the Wesfamers Centre of Vaccines & Infectious Diseases conducts.

Vaccine Trials Group

We are evaluating new vaccines for a range of diseases including influenza, pneumococcal, meningococcal and common infections such as otitis media (glue ear).

The PRIME Study

Vaccine Trials Group with Sir Charles Gairdner Hospital is conducting a trial of a vaccine against Clostridium difficile infection (CDI) in at-risk individuals.

RSV Study for Pregnant Mums

The study aims to determine whether an RSV vaccine given to pregnant women during the third trimester can protect newborn babies from RSV infections.

AusVaxSafety (previously FAST)

The aim of the study is the early identification of problems with the current flu vaccines, and providing parents and professionals with up to date information.

The Western Australian Influenza Vaccine Effectiveness Study (WAIVE)

The main objectives were to evaluate effectiveness of the annual flu vaccine in young children, and the burden of flu on young children and their families.