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Clinical studies supported by immunological data indicate early life intervention strategies to be promising in reducing the growing global burden of food allergies. The events that predispose to food allergy, including the induction of allergen-specific immune responses, appear to be initiated early in development.
Concepts of planetary health attempt to collectively address the biological, psychological, social, and cultural factors contributing to “Anthropocene Syndrome”, which encompasses the many wicked interrelated challenges of our time. It is increasingly evident that the wide array of causative factors is underpinned by attitudes, values, and worldviews.
Planetary health provides a perspective of ecological interdependence that connects the health and vitality of individuals, communities, and Earth's natural systems. It includes the social, political, and economic ecosystems that influence both individuals and whole societies.
The dramatic increase in the prevalence of allergic disease in recent decades reflects environmental and behavioural changes that have altered patterns of early immune development. The very early onset of allergic diseases points to the specific vulnerability of the developing immune system to environmental changes and the development of primary intervention strategies is crucial to address this unparalleled burden.
Maternal n-3 LCPUFA supplementation did not provide sustained effects on postnatal oxidative stress and telomere length as observed in the offspring
Review treatment and primary prevention studies, recent meta-analyses, and discuss the current understanding of the role of probiotics in this context
The microbiome is intimately connected to diet, nutrition, and other lifestyle variables
A better understanding of nutritional programming of immune health may lead to dietary strategies that reduce the burden of many inflammatory diseases
The implications of the microbiome extend to virtually every branch of medicine, biopsychosocial and environmental sciences
Develop evidence-based recommendations about the use of prebiotics in the prevention of allergy