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Applying spirometry phenotypes to a longitudinal cohort born very preterm

To better characterise prematurity-associated lung disease, adult spirometry phenotype classifications (obstructive lung disease, preserved ratio impaired spirometry and dysanapsis) have been applied to children born preterm. It is unknown how these phenotypes track over time.

Citation:
Bradshaw TK, Stanojevic S, Simpson SJ. Applying spirometry phenotypes to a longitudinal cohort born very preterm. BMJ Open Respir Res. 2026;13(1).

Keywords:
Lung Physiology; Paediatric Lung Disease; Paediatric Physician; Pulmonary Disease, Chronic Obstructive; Respiratory Function Test; Respiratory Measurement

Abstract:
To better characterise prematurity-associated lung disease, adult spirometry phenotype classifications (obstructive lung disease, preserved ratio impaired spirometry and dysanapsis) have been applied to children born preterm. It is unknown how these phenotypes track over time.