Effects of pregnancy and lactation prebiotics supplementation on infant allergic disease: A randomized controlled trial

Ingestion of prebiotics during pregnancy and lactation may have immunomodulatory benefits for the developing fetal and infant immune system and provide a potential dietary strategy to reduce the risk of allergic diseases. We sought to determine whether maternal supplementation with dietary prebiotics reduces the risk of allergic outcomes in infants with hereditary risk.

Citation:
Palmer DJ, Cuthbert AR, ……Pretorius RA, Garssen J, ……. Silva D, Prescott SL. Effects of pregnancy and lactation prebiotics supplementation on infant allergic disease: A randomized controlled trial. J Allergy Clin Immunol. 2024.

Keywords:
Allergy prevention; eczema; infant; lactation; maternal diet; prebiotics; pregnancy; randomized controlled trial

Abstract:
Ingestion of prebiotics during pregnancy and lactation may have immunomodulatory benefits for the developing fetal and infant immune system and provide a potential dietary strategy to reduce the risk of allergic diseases. We sought to determine whether maternal supplementation with dietary prebiotics reduces the risk of allergic outcomes in infants with hereditary risk.