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Searching for Strep A in the clinical environment during a human challenge trial: a sub-study protocol

Streptococcus pyogenes (also known as group A Streptococcus , Strep A) is an obligate human pathogen with significant global morbidity and mortality. Transmission is believed to occur primarily between individuals via respiratory droplets, but knowledge about other potential sources of transmission via aerosols or the environment is limited. Such knowledge is required to design optimal interventions to control transmission, particularly in endemic settings.

Citation:
Enkel SL, Hla TK, Wong B, Pickering J, Barnett TC, Thomas HMM, Lansbury N, Carapetis JR, Manning L, Bowen AC. Searching for Strep A in the clinical environment during a human challenge trial: a sub-study protocol. Access Microbiol. 2023;5(9) 

Keywords:
Streptococcus pyogenes; epidemiology; infection; transmission

Abstract:
Streptococcus pyogenes (also known as group A Streptococcus , Strep A) is an obligate human pathogen with significant global morbidity and mortality. Transmission is believed to occur primarily between individuals via respiratory droplets, but knowledge about other potential sources of transmission via aerosols or the environment is limited. Such knowledge is required to design optimal interventions to control transmission, particularly in endemic settings.