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Occurrence of psychosis and bipolar disorder in adults with autism: A systematic review and meta-analysis

Evidence suggests that individuals with autism spectrum disorder have increased rates of co-occurring psychosis and/or bipolar disorder. Considering the peak age of onset for psychosis and bipolar disorder occurs in adulthood, we investigated the co-occurrence of these disorders in adults with autism.

Citation:
Varcin KJ, Herniman SE, Lin A, Chen Y, Perry Y, Pugh C, Whitehouse A et al. Occurrence of psychosis and bipolar disorder in adults with autism: A systematic review and meta-analysis. Neurosci Biobehav Rev. 2022;134:104543.

Keywords:
Autism; Bipolar disorder; Psychosis; Risk factors; Schizophrenia spectrum disorders

Abstract:
Evidence suggests that individuals with autism spectrum disorder have increased rates of co-occurring psychosis and/or bipolar disorder. Considering the peak age of onset for psychosis and bipolar disorder occurs in adulthood, we investigated the co-occurrence of these disorders in adults with autism.